Hitaka, Takenori: search on Z-Library

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1

Synthesis of queuine, the base of naturally occurring hypermodified nucleoside (queuosine), and its analogues

Akimoto, Hiroshi, Imamiya, Eiko, Hitaka, Takenori, Nomura, Hiroaki, Nishimura, Susumu

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1988

Language:

english

File:

PDF, 843 KB

english, 1988

2

Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part I

Aikawa, Katsuji, Miyawaki, Toshio, Hitaka, Takenori, Imai, Yumi N., Hara, Takahito, Miyazaki, Junichi, Yamaoka, Masuo, Kusaka, Masami, Kanzaki, Naoyuki, Tasaka, Akihiro, Shiraishi, Mitsuru, Yamamoto,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

3

Design and synthesis of potent and selective pyridazin-4(1H)-one-based PDE10A inhibitors interacting with Tyr683 in the PDE10A selectivity pocket

Yoshikawa, Masato, Hitaka, Takenori, Hasui, Tomoaki, Fushimi, Makoto, Kunitomo, Jun, Kokubo, Hironori, Oki, Hideyuki, Nakashima, Kosuke, Taniguchi, Takahiko

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 810 KB

english, 2016

4

Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives

Asano, Moriteru, Hitaka, Takenori, Imada, Takashi, Yamada, Masami, Morimoto, Megumi, Shinohara, Hiromi, Hara, Takahito, Yamaoka, Masuo, Santou, Takashi, Nakayama, Masaharu, Imai, Yumi, Habuka, Noriyuk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 594 KB

english, 2017

5

Semisynthetic .BETA.-lactam antibiotics. 8. Structure-activity relationships of .ALPHA.-sulfocephalosporins.

NOMURA, HIROAKI, MINAMI, ISAO, HITAKA, TAKENORI, FUGONO, TAKESHI

Journal:

The Journal of Antibiotics

Year:

1976

Language:

english

File:

PDF, 4.76 MB

english, 1976

6

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

Tomohiro Kaku, Takenori Hitaka, Akio Ojida, Nobuyuki Matsunaga, Mari Adachi, Toshimasa Tanaka, Takahito Hara, Masuo Yamaoka, Masami Kusaka, Teruaki Okuda, Satoru Asahi, Shuichi Furuya, Akihiro Tasaka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

7

Semisynthetic .beta.-lactam antibiotics. 6. Sulfocephalosporins and their antipseudomonal activities

Nomura, Hiroaki, Fugono, Takeshi, Hitaka, Takenori, Minami, Isao, Azuma, Toshiyuki, Morimoto, Shiro, Masuda, Toru

Journal:

Journal of Medicinal Chemistry

Year:

1974

Language:

english

File:

PDF, 499 KB

english, 1974

8

Synthesis and Antitumor Activity of Pyrrolo(2,3-d)pyrimidine Antifolates with a Bridge Chain Containing a Nitrogen Atom.

ASO, Kazuyoshi, HITAKA, Takenori, YUKISHIGE, Koichi, OOTSU, Koichiro, AKIMOTO, Hiroshi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1995

File:

PDF, 1015 KB

1995

9

Discovery of 1-{4-[1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3- d ]pyrimidin-6-yl]phenyl}-3-methoxyurea (TAK-385) as a Potent, Orally Active, Non-Peptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor

Miwa, Kazuhiro, Hitaka, Takenori, Imada, Takashi, Sasaki, Satoshi, Yoshimatsu, Mie, Kusaka, Masami, Tanaka, Akira, Nakata, Daisuke, Furuya, Shuichi, Endo, Satoshi, Hamamura, Kazumasa, Kitazaki, Tomoyu

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.51 MB

english, 2011

10

Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists

Satoshi Yamamoto, Nobuyuki Matsunaga, Takenori Hitaka, Masami Yamada, Takahito Hara, Junichi Miyazaki, Takashi Santou, Masami Kusaka, Masuo Yamaoka, Naoyuki Kanzaki, Shuichi Furuya, Akihiro Tasaka, Ka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.58 MB

english, 2012

11

A novel synthetic approach to pyrrolo[2,3-d]pyrimidine antifolates

Miwa, Tetsuo, Hitaka, Takenori, Akimoto, Hiroshi

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 680 KB

english, 1993

12

Effect of an investigational CYP17A1 inhibitor, orteronel (TAK-700), on estrogen- and corticoid-synthesis pathways in hypophysectomized female rats and on the serum estradiol levels in female cynomolgus monkeys

Yamaoka, Masuo, Hara, Takahito, Araki, Hideo, Kaku, Tomohiro, Hitaka, Takenori, Tasaka, Akihiro, Kusaka, Masami

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.96 MB

english, 2013

13

Novel pyrrolo[2,3-d]pyrimidine antifolates: synthesis and antitumor activities

Miwa, Tetsuo, Hitaka, Takenori, Akimoto, Hiroshi, Nomura, Hiroaki

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 833 KB

english, 1991

14

Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys

Masuo Yamaoka, Takahito Hara, Takenori Hitaka, Tomohiro Kaku, Toshiyuki Takeuchi, Junzo Takahashi, Satoru Asahi, Hiroshi Miki, Akihiro Tasaka, Masami Kusaka

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.97 MB

english, 2012

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